Explores the Newly Discovered Link Between Nutrition and Epigenetics Current research suggests that nutrients are more than just food components and that certain nutrients can impact the expression of genes that lead to the development of chronic diseases. With contributions from experts in both fields, Nutrients and Epigenetics examines the epigenetic phenomena and the fascinating implications of diet on this largely uncharted field.Generously laden with tables and illustrations, many in color, this book addresses how nutrients alter physiologic and pathologic processes in the human body through epigenetic changes without affecting the DNA sequence. It also explains the detailed molecular structures of epigenetic phenomena and closely examines the current knowledge surrounding the biology of aging and embryonic growth regulation.Assesses the Likelihood of Clinical Applicability In one single compendium, this resource delineates the nutritional factors that further much-studied aberrant epigenetic patterns, such as DNA methylation, histone modifications, and chromatin remodeling. The book spotlights the influence of nutrition on epigenetic gene regulation, opening the way for counteracting future disease processes associated with epigenetic phenomena?a step that could potentially change the face of disease prevention and development.
The Cases You Need to Learn the Essential of Gynecologic Surgery Case Files: Gynecologic Surgery provides 40 clinical cases to illustrate evidence-based practice in the gynecologic surgery patient. Each case includes open-ended questions, extended discussion, Practice Pearls, a ?Controversy? discussion, comprehension questions, and references to the most current literature with a brief critique of each article. With this unique learning system you’ll learn how to become a better clinician in the context of real patients and the latest evidence-based medicine. Features * 40 high-yield clinical situations tailored for management and understanding of disease (pathophysiology) in the gynecologic surgery patient * Clear and easy-to-follow case-based format helps residents and fellows develop clinical thinking skills * Based on current journal articles and landmark studies, with an accompanying brief critique * “Practical Pearls” give evidence-based recommendations for patient management * “Controversy” feature discusses current controversies and different views related to each case * Multiple-choice comprehension questions accompany each case * Approximately 25 original drawings and clinical images enhance the text * Presents high-yield high-risk gynecologic surgery cases in an interactive and memorable format to help residents and fellows learn in the context of real patients * Proven learning system improves exam score
“Fletcher and Gardner have created a comprehensive resource that will be of interest not only to those working in the field of finance, but also to those using numerical methods in other fields such as engineering, physics, and actuarial mathematics. By showing how to combine the high-level elegance, accessibility, and flexibility of Python, with the low-level computational efficiency of C++, in the context of interesting financial modeling problems, they have provided an implementation template which will be useful to others seeking to jointly optimize the use of computational and human resources. They document all the necessary technical details required in order to make external numerical libraries available from within Python, and they contribute a useful library of their own, which will significantly reduce the start-up costs involved in building financial models. This book is a must read for all those with a need to apply numerical methods in the valuation of financial claims.”–David Louton, Professor of Finance, Bryant UniversityThis book is directed at both industry practitioners and students interested in designing a pricing and risk management framework for financial derivatives using the Python programming language.It is a practical book complete with working, tested code that guides the reader through the process of building a flexible, extensible pricing framework in Python. The pricing frameworks’ loosely coupled fundamental components have been designed to facilitate the quick development of new models. Concrete applications to real-world pricing problems are also provided.Topics are introduced gradually, each building on the last. They include basic mathematical algorithms, common algorithms from numerical analysis, trade, market and event data model representations, lattice and simulation based pricing, and model development. The mathematics presented is kept simple and to the point.The book also provides a host of information on practical technical topics such as C++/Python hybrid development (embedding and extending) and techniques for integrating Python based programs with Microsoft Excel.The book is accompanied by a CD ROM containing a code library; and a companion website www.wiley.com/go/fletcher_python which will feature code-based updates relating to Python 3.0.
For two decades, Dr. Danielle Ofri has cared for patients at Bellevue, the oldest public hospital in the country and a crossroads for the world’s cultures. In Medicine in Translation, she introduces us, in vivid, moving portraits, to the patients she has known. They have braved language barriers, religious and racial divides, and the emotional and practical difficulties of exile in order to access quality health care. Sharing their journeys with them over the years, Danielle has witnessed some of their best and worst moments, and come to admire their resilience and courageous spirit. Danielle introduces us to her patients: Samuel Nwanko, who was brutally attacked by a Nigerian cult in his homeland and is attempting to create a new life in America; Jade Collier, an Aussie who refuses to let a small thing like a wheelchair keep her from being a homegrown ambassador to New York City; Julia Barquero, a Guatemalan woman who migrated to the States to save her disabled son but cannot obtain the lifesaving heart transplant she needs because she is undocumented. We meet a young Muslim woman threatened at knifepoint for wearing her veil, and the spitfire Senora Estrella, one of Danielle’s many Spanish-speaking patients, whose torrent of words helps seal Danielle’s resolve to improve her own Spanish, an essential skill in today’s urban hospitals. And so she, her husband, and their two young children and seventy-five-pound dog relocate to Costa Rica, where they discover potholes the size of their New York City apartment, a casual absence of street signs or even street names, tangy green-skinned limon dulce dangling in the playground, and sudden rains surging over the craggy edges of roadside ditches. Ultimately, Danielle experiences being a patient in a foreign country when she gives birth to their third child, a “Costarricense” girl. With controversy over immigrants in our society escalating, and debate surrounding health-care reform becoming increasingly urgent, Ofri’s riveting stories about her patients could not be more timely. Living and dying in the foreign country we call home, they have much to teach us about the American way, in sickness and in health
The book focuses on a recently emerging topic in security. Specifically, the book focuses on physical layer security. Whereas conventional security mechanisms involve cryptography that operates at higher layers of the protocol stack, the methods described in this book secure communications at the physical layer.The area of physical layer security is an emerging field of research that has seen an explosion of research in the past few years. This trend is only expected to continue as there is a growing need to secure wireless communications without conventional cryptographic network security protocols.?The proposed book will consist of contributions from roughly a dozen of the leading research groups in this emerging area. For the first time, important results will be collected together. Important topics will include the secrecy rate of MIMO wireless systems, practical codes for the dissemination of secrets, and authentication of wireless transmitters using waveform-level properties.
Air pollution, global warming, and the steady decrease in petroleum resources continue to stimulate interest in the development of safe, clean, and highly efficient transportation. Building on the foundation of the bestselling first edition, Modern Electric, Hybrid Electric, and Fuel Cell Vehicles: Fundamentals, Theory, and Design, Second Edition updates and expands its detailed coverage of the vehicle technologies that offer the most promising solutions to these issues affecting the automotive industry.
Proven as a useful in-depth resource and comprehensive reference for modern automotive systems engineers, students, and researchers, this book speaks from the perspective of the overall drive train system and not just its individual components
Hieroglyphs were far more than a language. They were an omnipresent and all-powerful force in communicating the messages of ancient Egyptian culture for over three thousand years. This ancient form of expression was used as art, as a means of identifying Egyptian-ness, even for communication with the gods. In this exciting new study, Penelope Wilson explores the cultural significance of hieroglyphs with an emphasis on previously neglected areas such as cryptography and the continuing deciphering of the script in modern times. She covers topics like the origins of writing in Egypt, hieroglyphic script and the Egyptian language, hieroglyphs and art, scribes and everyday writing. She also examines the powerful fascination hieroglyphs still hold for us today. This book is the ideal reference for anyone with an interest in the fascinating civilization of Ancient Egypt
Use origami to make shirts and shorts for cards, scrapbooks, paper dolls, and gift packages.
Creating standards-compliant animations for the Web just got a lot easier. With this concise guide, you’ll learn how to convert Flash animations into HTML5, using Wallaby—the experimental tool from Adobe. Wallaby makes Flash content available for devices that don’t support Flash runtimes, including the iPhone and iPad.
Developing HTML5 animations is time-consuming with all the coding required. This book shows you how to create compelling content for HTML5 environments with relative ease, whether you know Flash or not. After a quick introduction to simple animation building with Flash, you’ll learn how Wallaby helps you convert those animations into HTML5 code.
Perhaps the hardest thing about following Christ is translating our good intentions into deeds. Christ calls us, and we yearn to answer him, but time and again we lose resolve. Is discipleship possible amid the stresses of modern life? Can Christ bring about lasting change in our lives? How can we be centred on him, when everything seems to pull us apart? This book offers hard-won insights into the challenges of living for Christ in the nitty-gritty of daily life. Many of the selections offer answers to specific needs or problems. Others grapple with broader themes such as the importance of community. All of them pulsate with conviction and compassion, and all of them readiate hope